The Leech saliva reveals the presence of a variety of BIOACTIVE PEPTIDES and PROTEINS involving:

Antithrombin (hirudin, bufrudin),

Antiplatelet (calin, saratin),

Factor Xa inhibitors (lefaxin),

Antibacterial (theromacin, theromyzin) and others.

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Leech Therapy is beneficial for:

Cardiovascular diseases, plastic surgery, diabetes mellitus, high blood pressure, arthritis, ear and hearing problems, hepatitis, kidney diseases, skin diseases, nervous system abnormalities, urinary and reproductive system problems, inflammation, vascular diseases, venous diseases, sports injuries, dental problems, epilepsy, brain congestion, acute gastritis, hypertension and eye illnesses, gout, headache, whooping coughs, ischemia, gonarthritis, hemorrhoids, cancer, metastasis, infectious diseases and the

SUPERB BENEFICIAL usage of leeches in the management of coronary thrombosis.

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HIRUDIN is more effective than HEPARIN (Heparin is used to prevent blood clots from forming in people with certain medical conditions).

Studies revealed that hirudin is more effective than heparin in preventing deep venous thrombosis (DVT) and ischemic events in patients with unstable angina.

 

HIRUDIN has the advantage of exerting a direct inhibitory effect on thrombin without the need for endogenous cofactors. 

Unlike heparins, hirudin has promising prophylactic activity in patients who are at a high risk of developing cardiovascular events because it can hinder thrombus growth due to its ability to block thrombin-fibrin binding. Consequently, it was reported that hirudin can reduce DVT, pulmonary embolism, and the spread of venous thrombosis

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* Preventing the blocking of arteries and veins

* Vasodilating effect (widens the blood vessels)

* Thrombolytic effect (blood clots dissolving effect)

* Anti-inflammatory effect

* Antiseptic effect, stops the growth of microorganisms and bacteria

* Blood circulation improvement

* Risk of stroke and heart attack is reduced and a

* NOTICEABLE BOOST OF YOUR IMMUNE SYSTEM

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Leech can suck blood from deep veins which cannot be reached by the conventional wet cupping.

Hirudin is the only hematophagous animal-derived anticoagulant that has been approved by FDA for clinical purposes.

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• Can reduce blood hypercoagulability with an anti-inflammatory effect in patients with thrombophlebitis, likewise, patients with phlebitis who received topical leeching exhibited better walking ability, less pain, and minor leg swelling, along with near-normal leg skin colour.

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• Factor Xa was identified to play a key role in the human body's hemostasis.

• A promising tool for Fibrinogenolytic

• Leech saliva could be more powerful as an antimetastatic drug

• The salivary gland secretion of the proboscis leech could suppress metastasis of melanoma, breast cancer, lung cancer, and prostate cancer and

• Hirudin preparation as an efficacious metastasis inhibitor of a wide range of malignant tumor cells, such as pulmonary carcinoma, breast carcinoma, bladder carcinoma, colorectal carcinoma, soft-tissue sarcoma, leukemia, and lymphoma

• 17-kDa protein, called antistasin, has the capability to prevent lung cancer colonization

• Hirudo medicinalis can completely cure the local lumbar pain in patients with advanced stages of renal cancer and leiomyosarcoma

• H. manillensis display an antiproliferative activity in vitro against small cell lung cancer

• Leech therapy as an antihyperglycemic medication

• Hirudin plays an essential role in preventing the clotting process because of its ability to bind thrombin and consequently suppress the thrombin-mediated conversion of fibrinogen into fibrin enabling it to be efficacious for the relieving of ischemic events

• Calin, isolated from H. medicinalis, has been proven to obstruct the formation of thrombi as described above and paramount benefits to diabetic patients

• Antibiotical and antibacterial effect against both Gram-positive and Gram-negative strains

• Beneficial usage of the leech extract in cleaning products for hospital disinfection and the daily domestic cleaning

• Painkilling effect in patients with osteoarthritis, disability improvement reduced stiffness and inflammation in arthritis

• Leech therapy as an analgesic for iliosacral joints pain and cervicobrachialgia syndrome

• Remedy for abscess, treatment of tinnitus, acute and chronic otitis