Science on Wet Cupping


Wet Cupping improves the amount of 

NK Cell and T CD8+ for an improved and stronger immune system.

Leech Therapy for Chronic Wound Healing
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Wet Cupping improves Immunology Function 
  • clears interstitial fluids

  • enhances skin and body function

  • improves lymphatic flow

  • restoring homeostasis

  • improves capillary circulation

  • hyperemia

  • cellulitis

  • fibromyalgia

  • carpal tunnel syndrome

  • migraine

  • hypertension

  • rheumatoid arthritis

  • chronic pain relief

  • filtration and cleaning of capillaries

      (at both ends)


Science on Wet Cupping 

Blood loss due to Wet Cupping treatment does not cause health hazards after several treatments, "No Significant changes in the blood levels for all the good stuff your body blood needs.

  • reduces Cholesterol

  • prevention and control of Diabetes

  • prevention and control for Kidney Diseases

  • reduces hardening of Arteries

  • reduces Hyperlipidemia

  • reduces Hyperglycemia

  • Hypertension

  • Headache

  • Chest pain

  • Muscle aches

  • Depression

  • Anxiety

  • Psychological disorder

  • Metabolic disorder

Wet Cupping Therapy has an excretory effect on the Kidney
and reduce the overload of Heavy Metals and Toxic Metals in the bloodstream also proves the activation of

Neurohormones produced in the Hypothalamus as well as improvement of Endocrine and Nervous System functions.

  • Smokers

  • Cholesterol/ LDL

  • Hypertension/ high blood pressure

  • Chronic tension/ migraine, headache

  • Carpal tunnel syndrome (CTS), pinched nerve

  • Pathophysiological disorder associated with injury and diseases

  • Brachialgia paresthetica nocturna

  • Nerve pain

  • Bronchial Asthma

  • Rheumatoid Arthritis

  • Herpes Zoster

  • Cardiovascular diseases and prevention

  • Psoriasis

Evidence and benefits of Wet Cupping Therapy, hijama cupping.
Wet Cupping effective in the treatment of Herpes Zoster
Wet Cupping Therapy Improves the Parameters of Ventricular Repolarization
  • cardiac electrophysiology
  • cardiac activity 
  • cardioprotective effects
  • alleviates symptoms of various diseases
  • hormonal adjustments 
  • anti- inflammatory effect 
  • decreases pain/ chronic 
  • positive effect in biomechanics of skin ( collagen and elastin)
  • changes in tissue structure 
  • increases blood circulation 
  • relaxation in muscle 
  • loosens adhesion and fascia 
  • activates the peripheral neural network 
  • removes toxins and fluids
  • removes uric acid, Lipoprotein, serum glutamic oxalacetic transaminase, iron and heavy metals
  • blood detoxification 
  • chronic acute inflammation 
  • contagious diseases
  • autoimmune disorders 
  • rehabilitation of stroke
  • hypertension
  • highly effective treating musculoskeletal pain 
  • Tension and headache 
  • boosts the cutaneous and muscular flow 
  • modulates immune system 
  • beneficial effect on the immune system 
  • improvement of the nervous system 
  • release of B-endorphin and adrenocortical hormones 
  • blocks arthritis inflammation and removal 
  1. Pain-gate theory 
  2. Immune system activation theory 
  3. Nitric oxide release theory

Encouragement to clinicians as an add-on therapeutic option in cardiac arrhythmias. 

Prevention and control of Diabetes Mellitus, Kidney diseases, and additional, not detrimental to vital fluids

Significantly reduces:
  • Chest pain
  • Hypertension/ Headache
  • Muscle aches
  • Cholesterol 

  • Hyperlipidemia
  • Hyperglycemia

Additional regulating:                                                        
  • Hormones                                                                 
  • Autonomic nervous system
  • Rheumatoid Arthritis 
  • Physiological function 
  • The count of red blood cells
  • Pulmonary disease 
  • Cell repair
  • Enhancing the immune system
  • Lymphocytes
  • Cholesterol LDL
  • Hypertension/ HBP
  • Diabetes, sugar, and urea levels

Effective for: 
  • Gallbladder stones 
  • Kidney stones 
  • Headache 
  • Migraine
  • Oral ulcers
  • Genital ulcers 
  • Cardiovascular disease 
  • Atherosclerosis 

Wet Cupping induces Anti-inflammatory action in vigorous Martial Art Athletes 

Wet Cupping reduces pain, headache, and disability in patients with migraines 
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Wet Cupping using different techniques 
for lower back pain

  • Foundings sharp decrease and/ no pain for lower back pain
  • Improving disability in patients with Chronic Low Back Pain 

Wet Cupping is effective for different types of headaches 

  • Fibromyalgia 
  • Gouty arthritis 
  • Facial paralysis 
  • Hyperlipidemia 
  • Hypercholesterolemia 
  • Cough 
  • Asthma 
  • Acne 
  • Atopic dermatitis 
  • Idiopathic urticaria 

Viral infections:
  • Herpes zoster 
  • Viral hepatitis 
Bacterial infections:
  • Cellulitis
  • Porphyria cutaneatarda 
  • Sickle cell disease 
  • Fatty liver disease with Hyperferritinemia
  • Myelitis
  • Neuralgia 
  • Relives congestion and swelling
  • Declining toxins 
  • Reinstate neuroendocrine balance and hemostasis 
  • Relieves muscle spasms 
  • Increases oxygen supply 
  • Improves tissue 
  • Decreases free radicals and oxidative stress
  • Mobilizing QI Energy flow
  • Regulating body function activation of the Primo vessel system, blood and lymph vessels, nerves, viscera, and FASCIA. 
  • Activation of the spinal cord and brain for vital energy flow 
  • Balancing heart, brain, liver, lymph, and blood vessel connections

Wet Cupping removes Oxidants and decreases Oxidative Stress
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Wet Cupping filters hydrophobic and hydrophilic substances under higher filtration pressure leading to a higher quality of blood volume and decreasing pressure. 
Stimulating the release of Endogenous opioids (Peptises)
  • Lymph circulation and drainage  
  • Immunity 

  • Sympathetic system 
  • BAT
  • Clearing of plasma liquids
  • Activation of cyclooxygenase 
  • Vitalization of the whole body
  • Removing toxins and waste materials 
  • Antiarrhythmic effects 
  • Capillary venous returns
  • Patients general feel-good effect after Wet Cupping
  • Blood flow 
  • Oxygen supply
  • Tissue perfusion 

  • Inflammation 
  • Iron overload 
  • Intestinal fluid pressure
  • Venous pressure 
  • Congestion
  • Swelling 

  • Cardiac dysrhythmia
  • Cardiac protection
  • Protecting heart and brain from accumulation of waste materials and stagnation
  • Peripheral vascular resistance
  • Releasing trapped energy (QI) 
  • Chinese meridians activation and unlocking
  • Restoring Neuroendocrine and hemostasis balance
  • Modulate Angiogenesis 
  • Relives muscle spasms
Wet Cupping Therapy is effective for reducing Systolic Blood Pressure in hypertensive patients for up to 4 weeks, without serious side effects and considered as a complementary hypertension treatment
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Therapeutic effect on shoulder pain and neck pain 
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Microparticle clearance theory as a Novel Mechanism through which Wet Cupping Therapy may exert Anti-inflammatory, Anti-thrombotic and afford Endothelial Protection within tissues microvasculature. 

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Brachialgia Paraesthetica Nocturna can be relieved by WET CUPPING

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A new remedial approach to oxidant/antioxidant imbalance-based diseases: Wet Cupping Therapy
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Continuing Medical Education for Wet-Cupping Providers
The Efficacy of Wet Cupping in treatment of Hypertension
The effectiveness of wet cupping on diseases: A systematic review of randomized controlled
Wet Cupping Therapy effective for Chronic Urticaria
Highly effective in treating pain, tension headache, musculoskeletal pain and useful for a wide range of systematic conditions
  • Cold
  • Cough 
  • Asthma
  • Stroke rehabilitation 
  • Acne 
  • Removing toxins 
  • Cholesterol reducing
  • Improves blood pressure
  • Stimulating the nervous system 
  • Modulates the immune system 
Reducing Cortisol Levels in Arabian Horses 
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Effectiveness of Wet Cupping for Facial Acne 
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Effectiveness of Cupping for Infertility

After 28 sessions, the patient’s general condition improved significantly; she felt less anxiety and her sleep improved. Finally, she became pregnant naturally and gave birth to a son.
Facelift and Facial Rejuvenation
  • fresher and younger look
  • increased collagen production and elastin 
  • firmer skin
  • erasure of fine lines and reduction of deeper lines
  • activation of the lymphatic system 

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  1. Pain-Gate Theory (PGT)

  2. Diffuse Noxious Inhibitory Controls (DNICs)

  3. Release of Nitric Oxide theory

  4. Reflex Zone Theory

  5. Activation of Immune System Theory

  6. Blood detoxification theory

Wet Cupping for female infertility


Out of 59 women,

12 patients (20.3%) became pregnant after Wet Cupping. 

19 partners of 40 of those women had oligospermia/ low sperm count (male condition). 

Only the females were treated with Wet Cupping Therapy in this study. 

  • Wet Cupping can induce regular ovulation in females with polycystic ovarian syndrome (PCOS)

Male with Primary Infertility

Wet cupping therapy in a male with primary infertility.

Wet cupping therapy can be effective in treating individuals with infertility.

He presented with complaints of inability to get his wife pregnant and premature ejaculation for the past 7 years despite having regular and unprotected sexual intercourse. He was confirmed infertile in a hospital.

The wife of the man became pregnant after 2 months of wet cupping therapy.

Cupping for Constipation in children 
Cupping is effective in relieving Insomnia Symptoms 
Leech Therapy is beneficial in the reduction of pain, tenderness, stiffness, crepitus, and swelling in the patients of osteoarthritis.
Leech Therapy for nonhealing venous ulcer in systemic sclerosis. 
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Leech Therapy for Chronic Low Back Pain
Benefits of Leech salvia (LSE, protein, and enzymes)

The salvia is beneficial for:

  • cancer

  • skin disorders

  • arthritis

  • elimination of microcirculation disorders

  • removing hypoxia 

  • restoring organs and tissues

  • decreasing blood presser

  • detoxifying

  • increased immune system 

  • pain manager 

  • priapism 

  • macroglossia

  • wounds and many others

  • relief from the hostile complications like strokes and infarct, and the organism’s bioenergetic status improvement

Leech Salvia ​contains

Hirudin: Anticoagulant (blood thinner)

Hyaluronidase: Possesses antibiotic futures, Hyal associated with Hyaluronic acid HA and HA motivates the spreading, migration, attack and cancer cells metastasis. 

Destabilase: Enzyme possessing glycosidase activity. Showing both fibrinolytic and antibacterial actions and stabilizing fibrins. 

Eglin C: Contains 70 amino acids, powerful prevents chymase, alpha chymotrypsin, subtilisin, elastase and cathepsin G. Eglin C is a therapeutic agent against various pathogenic elastic tissue agents, blood clotting disorders and inflammatory processes. Valuable in diseases induced by neutral granulocytic proteinases. 

Factor Xa Inhibitor: Hinders Xa activity it plays a vital role in arthritis and osteoarthritis. 

Hirustasin: Contains 55 amino acids peptides and most elementary proteinase inhibitors: 

Trypsin, chymotrypsin and neutrophil cathepsin. Contributes to normal blood pressure and can be applied as an antimetastatic protein with no anticoagulant

effect n colorectal cancer and breast cancer. 

Bdellins: Antiinflammatory effect and hinders plasmin, trypsin and acrosin. Anticoagulant!

MLT is not suggested in cases with hemorrhagic diathesis, leukemia, bone marrow suppression, anticoagulant therapy, cirrhosis, dialysis, radiotherapy, and chemotherapy.

Immediate and Delayed Effects of Cupping Therapy on Reducing Neuromuscular Fatigue
Wet Cupping therapy for sudden Sensorineural Hearing Loss and Tinnitus.
Significant hearing improvement across almost all frequencies
Nonalcoholic fatty liver disease (NAFLD) is known to be the most prevalent chronic liver disease all over the world.
Improvement in fatty liver severity and improved HOMA-IR and liver enzymes in patients with NAFLD through Hijama, Wet cupping. 
Bleeding and cupping 
Wet Cupping for patients presenting with orthopedic type pain 
Leech Therapy for Chronic Low Back Pain
Controlling Type II Diabetes Mellitus with cupping method
Cupping treatments had sustainable effects on physical function and quality of life for up to 2 years in patients with chronic neck pain. 
Cupping therapy for multiple sclerosis 
Wet Cupping in combination with acupotomy for reducing lumbar disc herniation
World Congress Integrative Medicine & Health 2017
Wet cupping is a leading traditional therapy in Asia and the Middle East as a part of the traditional healing system.
Highlighting the Saudi Governmental experience in regulating and integrating Wet Cupping in conventional health care.
Taking wet cupping therapy beyond research stages. 
Wet Cupping therapy exerts cardioprotective, tissue-protective, and immune potentiating effects in thalassemic children.


due to iron overload, increased oxidative stress, atherogenic lipid profile, and tissue damage. 
Hashimoto Thyroiditis, Thyroid gland, Thyroiditis 

Effects of Wet Cupping on autoimmune activity and thyroid hormonal profiles of  Hashimoto's disease (HD patients). 

Improvement and positive changes in regaining of gland physiological size, echogenicity, and vascularity. 

Changes in anti- TPO and anti- TG showed a decrease. A significant decrease in levels of anti-TPO, anti-TG, TSH, prolactin, and erythrocyte sedimentation rate (ESR) occurred.

The efficacy of Hijama on the pathogenesis of HD in modulating the immune-inflammatory process demonstrated by the reduction in ESR, TPO, and TSH levels on a fixed thyroxin supplementation dose, along with patient-reported clinical improvement and positive changes in ultrasound including regaining of gland physiological size, echogenicity, and vascularity.

Wet Cupping mimics an artificial kidney.

Where an in vivo kidney filters hydrophobic materials through the glomeruli via normal pressure filtration,
Wet Cupping filters both hydrophilic and hydrophobic material through high-pressure filtration.
The high pressure from suction leads to increased blood volume, increased capillary filtration rate, and the expulsion of filtered and interstitial fluid in the area.
Filtered fluid collected contains disease-related and disease-causing substances as well as prostaglandins and inflammatory mediators.
The scratches made with the scalpel increase innate and acquired immunity by stimulating inflammatory cell migration and endogenous opioid release.
This action leads to improved blood flow, removal of toxins, restored neuroendocrine balance, improved oxygen supply, and tissue perfusion.
Wet Cupping therapy significantly improves menstrual cycles and can induce menstrual bleeding in (PCOS) polycystic  syndrome patients
Wet Cupping therapy significantly enhanced CE, O2 saturation, BP and PR in sedentary male smoker students.
Wet Cupping showed improvements in all measurements with a high statistically significant difference (p<0.05).

Increased sympathetic stimulation in smokers may be a risk factor for pulmonary and cardiovascular diseases.
The study was conducted to assess the immediate effect on blood pressure (BP), oxygen (O2) saturation, chest expansion (CE), pulse rate (PR) in sedentary male smoker students.